Laboratory of Nanomedicine and Healthcare Biomaterials

Welcome to our lab at NJIT.

Who are we?

We explore the interface of biomaterials and medicine using chemistry, materials science and engineering.

From lipid nanoparticles (LNPs) to membrane-hybrid nanovaccines, engineered for delivery and safety.

mRNA, siRNA, and logic-gated constructs paired with rational delivery for targeted expression.

Hollow-fiber–based continuous production with tunable mixing, size control, and high throughput.

We develop multifunctional biomaterials for medical applications and study structure–function relationships.

LNPs and vesicles optimized for biodistribution, stability, and endosomal escape.

Injectable gels and bioactive matrices enabling regeneration and controlled release.

Correlating composition, assembly, and microstructure with in vitro/in vivo performance.

2025-10-01 Dr. Xu’s group and Dr. Zhang’s group collaborated to publish the manuscript “Computationally Aided Design of Ionizable Cholesteryl Lipids for Lipid Nanoparticles to Modulate Hepatic mRNA Accumulation” in Journal of the American Chemical Society. Great job!
2025-10-01 Dr. Xu’s group and Dr. Zhang’s group collaborated to publish the manuscript “Computationally Aided Design of Ionizable Cholesteryl Lipids for Lipid Nanoparticles to Modulate Hepatic mRNA Accumulation” in Journal of the American Chemical Society. Great job!
2025-09-01 Under the leadership of Dr. Chad Mirkin, Dr. Xu and many other professors published “33 Unresolved Questions in Nanoscience and Nanotechnology” in ACS Nano. Congratulations!